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RESEARCH IN FOCUS

Explore OPRI’s collection of published research on Oral Corticosteroid (OCS) use

PUBLICATIONS DATABASE

Patterns of Care in the Management of High-Risk COPD in the US (2011-2019): An Observational Study for the CONQUEST Quality Improvement Program

The Lancet Regional Health – Americas

31 July 2023

Margee Kerr, Yasir Tarabichi, Alexander Evans, Douglas Mapel, Wilson Pace, Victoria Carter, Amy Couper, M. Bradley Drummond, Norbert Feigler, Alex Federman, Hitesh Gandhi, Nicola A. Hanania, Alan Kaplan, Maja Kruszyk, Marije van Melle, Hana Müllerová, Ruth Murray, Jill Ohar, Michael Pollack, Rachel Pullen, Dennis Williams, Juan Wisnivesky, MeiLan K Han, Catherine Meldrum, David Price, Kostas Kostikas

Impact of Initiating Biologics In Patients with severe asthma and on Long-Term OCS Or Frequent Rescue Steroids

Journal of Allergy and Clinical Immunology: In Practice

8 June 2023

Wenjia Chen, Trung N Tran, Mohsen Sadatsafavi, Ruth Murray, Nigel Chong Boon Wong, Nasloon Ali, Cono Ariti, Lakmini Bulathsinhala, Esther Garcia Gil, Mark FitzGerald, Marianna Alacqua, Mona Al-Ahmad, Alan Altraja, Riyad Al-Lehebi, Mohit Bhutani, Leif Bjermer, Anne Sofie Bjerrum, Arnaud Bourdin, Anna Von Bülow, John Busby, Giorgio Walter Canonica, Victoria Carter, George Christoff, Borja G Cosio, Richard Costello, João A Fonseca, Peter G. Gibson, Liam Heaney, Enrico Heffler, Mark Hew, Ole Hilberg, Flavia Hoyte, Takashi Iwanaga, David Jackson, Rupert Jones, Piotr Kuna, Désirée Larenas Linnemann, Sverre Lehmann, Lauri Lehtimäki, Juntao Lyu, Bassam Mahboub, Andrew Menzies-Gow, Anthony Newell, Concetta Sirena, Nikolaos Papadopoulos, Andriana Papaioannou, Diahn-Warng Perng (Steve), Matthew Peters, Celeste Porsbjerg, Todor Popov, Chin Kook Rhee, Sundeep Salvi, Camille Taillé, Christian Taube, Carlos Arturo Torres-Duque, Charlotte Suppli Ulrik, Seung Won Ra, Eileen Wang, Michael Wechsler, David Price, Mariko Koh, Jorge Máspero, Kwang Ha Yoo, Luis Perez de Llano, Paul E Peffler

Data Resource Profile: Optimum Patient Care Research Database (OPCRD)​

Pragmatic and Observational Research

27 April 2023

Anita Lynam, Charlotte Curtis, Brooklyn Stanley, Heath Heatley, Chloe Worthington, Emma-Jane Roberts, Chris Price, Victoria Carter, John Dennis, Andrew McGovern, David Price

Heterogeneity of asthma–chronic obstructive pulmonary disease (COPD) overlap from a cohort of patients with severe asthma and COPD

Therapeutic Advances in Respiratory Disease

25 April 2023

Joon Young Choi, Chin Kook Rhee, Kwang Ha Yoo, Ki-Suck Jung, Jae Ha Lee, Hyoung Kyu Yoon, Seung Won Ra, Myung Goo Lee, Yong Suk Jo

Identification of key opportunities for optimising the management of high-risk COPD patients in the UK using the CONQUEST Quality Standards: an observational longitudinal study

The Lancet Regional Health – Europe

21 April 2023

David Halpin, Andrew P. Dickens, Derek Skinner, Ruth Murray, Mukesh Singh, Katherine Hickman, Victoria Carter, Amy Couper, Alexander Evans, Rachel Pullen, Shruti Menon, Tamsin Morris, Hana Müllerová, Mona Bafadhel, James Chalmers, Graham Devereux, Martin Gibson, John Hurst, Rupert Jones, Jennifer Quint, Dave Singh, Marije van Melle, Tom Wilkinson, David Price, Kostas Kostikas

Application of an algorithm to analyse patterns of intermittent oral corticosteroid use in asthma

NPJ Primary Care Respiratory Medicine

4 March 2023

John Haughney, Trung N Tran, Heath Heatley, Arnaud Bourdin, Andrew Menzies-Gow, David Jackson, Ekaterina Maslova, Jatin Chapaneri, Derek Skinner, Victoria Carter, Jeffrey Shi Kai Chan, David Price

Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in patients with severe asthma eligible for both (FIRE)

Allergy

28 February 2023

Paul Pfeffer, Nasloon Ali, Ruth Murray, Charlotte Ulrik, Trung Tran, Jorge Maspero, Matthew Peters, George Christoff, Mohsen Sadatsafavi, Carlos A. Torres-Duque, Alan Altraja, Lauri Lehtimäki, Nikolaos Papadopoulos, Sundeep Salvi, Richard W. Costello, Breda Cushen, Enrico Heffler, Takashi Iwanaga, Mona Al-Ahmad, Désirée Larenas-Linnemann, Piotr Kuna, João Fonseca, Riyad Al-Lehebi, Chin Kook Rhee, Luis Perez de Llano, Diahn-Wang Perng, Bassam Mahboub, Eileen Wang, Yun Yi Celine Goh, Juntao Lyu, Anthony Newell, Marianna Alacqua, Mohit Bhutani, Leif Bjermer, Unnur Steina Björnsdóttir, Arnaud Bourdin, Anna Von Bülow, John Busby, Walter Canonica, Borja G Cosio, Delbert Dorscheid, Mariana Muñoz Esquerre, Mark FitzGerald, Esther Garcia Gil, Peter Gerard Gibson, Liam Heaney, Mark Hew, Ole Hilberg, Flavia Hoyte, David Jackson, Mariko Koh, Hsin-Kuo Ko, Jae Ha Lee, Sverre Lehmann, Claudia Chaves Loureiro, Dora Ludviksdottir, Andrew Menzies-Gow, Patrick Mitchell, Andriana Papaioannou, Todor Popov, Celeste Porsbjerg, Laila Salameh, Concetta Sirena, Camille Taillé, Christian Taube, Yuji Tohda, M. E. Wechsler, David Price.

The association between short-acting β2-agonist over-prescription, and patient-reported acquisition and use on asthma control and exacerbations: data from Australia

Advances in Therapy

26 February 2023

David Price, Christine Jenkins, Bruce Willett, Eric Bateman

An Observational UK cohort study to describe intermittent oral corticosteroid prescribing patterns and their association with adverse outcomes in asthma

Thorax

27 December 2022

Heath Heatley, Trung N Tran, Arnaud Bourdin, Andrew Menzies-Gow, David Jackson, Ekaterina Maslova, Jatin Chapaneri, Derek Skinner, Victoria Carter, Jeffrey Shi Kai Chan, Cono Ariti, John Haughney, David Price

Patients with chronic obstructive pulmonary disease and evidence of eosinophilic inflammation experience exacerbations despite receiving maximal inhaled maintenance therapy

International Journal of Chronic Obstructive Pulmonary Disease

8 November 2022

Stephanie Chen, Marc Miravitlles, Chin Kook Rhee, Rupert Jones, Victoria Carter, Benjamin Emmanuel, Marianna Alacqua, David Price, Ian Pavord

Characterization of patients in the International Severe Asthma Registry with high steroid exposure who did or did not initiate biologic therapy (GLITTER I)

Journal of Asthma and Allergy

21 October 2022

Wenjia Chen, Mohsen Sadatsafavi, Trung N Tran, Ruth Murray, Nigel Chong Boon Wong, Nasloon Ali, Cono Ariti, Esther Garcia Gil, Anthony Newell, Marianna Alacqua, Mona Al-Ahmad, Alan Altraja, Riyad Al-Lehebi, Mohit Bhutani, Leif Bjermer, Anne Sofie Bjerrum, Arnaud Bourdin, Lakmini Bulathsinhala, Anna Von Bülow, John Busby, Giorgio Walter Canonica, Victoria Carter, George Christoff, Borja G Cosio, Richard Costello, Mark FitzGerald, João A Fonseca, Liam Heaney, Enrico Heffler, Mark Hew, Ole Hilberg, Flavia Hoyte, Takashi Iwanaga, David Jackson, Rupert Jones, Piotr Kuna, Désirée Larenas Linnemann, Sverre Lehmann, Lauri Lehtimäki, Juntao Lyu, Bassam Mahboub, Andrew Menzies-Gow, Concetta Sirena, Nikolaos Papadopoulos, Andriana Papaioannou, Diahn-Warng Perng (Steve), Matthew Peters, Celeste Porsbjerg, Todor Popov, Chin Kook Rhee, Sundeep Salvi, Camille Taillé, Christian Taube, Carlos Arturo Torres-Duque, Charlotte Suppli Ulrik, Seung Won Ra, Eileen Wang, Michael Wechsler, David Price, Mariko Koh, Jorge Máspero, Kwang Ha Yoo, Luis Perez de Llano, Paul E Peffler

Effect of stepping up to high-dose inhaled corticosteroids in patients with asthma

Journal of Allergy and Clinical Immunology

11 September 2022

Trung N Tran, Rupert Jones, Javier Nuevo, Maarten van den Berge, Guy Brusselle, Andrew Menzies-Gow, Derek Skinner, Victoria Carter, Janwillem Kocks, David Price, Ian Pavord

A pragmatic primary practice approach to allergy testing in asthma diagnosis, management, and referral

Journal of Asthma and Allergy

16 August 2022

Pascal Demoly, Andrew H. Liu, Pablo Rodriguez del Rio, Soren Pedersen, Thomas Casale, David Price

Asthma Exacerbations are Associated with a decline in Lung Function: A Longitudinal Population-Based Study

Thorax

3 August 2022

Seyi Soremekun, Liam Heaney, Derek Skinner, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Ruth Murray, Trung N Tran, Benjamin Emmanuel, Esther Garcia Gil, Andrew Menzies-Gow, Matthew Peters, Njira Lugogo, Rupert Jones, David Price, Naeimeh Hosseini, Neva Eleangovan

Characterisation of the Australian adult population living with asthma: Exacerbation frequency, long-term OCS use and adverse effects

Pragmatic and Observational Research

25 July 2022

Sinthia Bosnic-Anticevich, Mark Hew, Li Ping Chung, Biljana Cvetkovski, Scott Claxton, Peter Del Fante, Eve Denton, Joe Doan, Kanchanamala Ranasinghe, Lucy Morgan, Anita Sharma, Peter Smith, Deb Stewart, Philip J Thompson, Russell Wiseman, John Upham, Kwok Y Yan, Victoria Carter, Kiranjeet Dhillon, Florian Heraud, Thao Le, Rebecca Vella, David Price, John D Blakey, Kerry Hancock

Characterization of COPD in U.S. primary care: data from the Optimum Patient Care with DARTNet Research Database and the embedded Advancing the Patient Experience (APEX) in COPD registry

The Annals of Family Medicine

20 July 2022

Wilson Pace, Elias Brandt, Victoria Carter, Ku-Lang Chang, Chelsea Edwards, Alexander Evans, Chester Fox, Gabriela Gaona, MeiLan K Han, Alan Kaplan, Rachel Kent, Janwillem Kocks, Maja Kruszyk, Chantal Le Lievre, Tessa Li Voti, Cathy Mahle, Barry Make, Amanda Ratigan, Asif Shaikh, Neil Skolnik, Brooklyn Stanley, Barbara P Yawn, David Price

Biologics in severe asthma: the role of real-world evidence from registries

Eur Respir Rev

7 June 2022

Giovanni Paoletti, Jack Pepys, Marta Casini, Danilo Di Bona, Enrico Heffler, Celine Y.Y. Goh, David B. Price, Giorgio Walter Canonica

Variation in demographic and clinical characteristics of Patients with COPD receiving care in U.S. primary care: data from the Advancing the Patient EXperience (APEX) in COPD registry

Pragmatic and Observational Research

29 April 2022

Chester Fox, Wilson Pace, Elias Brandt, Victoria Carter, Ku-Lang Chang, Chelsea Edwards, Alexander Evans, Gabriela Gaona, MeiLan K Han, Alan Kaplan, Rachel Kent, Janwillem Kocks, Maja Kruszyk, Chantal Le Lievre, Tessa Li Voti, Cathy Mahle, Barry Make, Amanda Ratigan, Asif Shaikh, Neil Skolnik, Brooklyn Stanley, Barbara P Yawn, David Price

CONQUEST: a quality improvement program for defining and optimizing standards of care for modifiable high-risk COPD patients

Patient Related Outcome Measures

23 February 2022

Luis Alves, Rongchang Chen, Mark Dransfield, John Hurst, Fernando Martinez, Marc Miravitlles, Shigeo Muro, David Singh, Anita Sharma, Tonya Winders, Jonathan Marshall, Clementine Nordon, Michael Pollack, David Jones, Rupert Jones, Ruth Murray, Margee Kerr, Marije van Melle, Antony Hardjojo, Victoria Carter, Alexander Evans, Amy Couper, Rachel Pullen, Chris Price, David Price, Kostas Kostikas

Pub Med

Comparative safety of extrafine beclometasone fixed dose combinations (FDC) and fluticasone FDC in COPD

International Journal of Chronic Obstructive Pulmonary Disease

15 February 2022

David Price, William Henley, José Eduardo Delfini Cançado, Leonardo M. Fabbri, Huib AM Kerstjens, Alberto Papi, Nicolas Roche, Elif Şen, Dave Singh, Claus Vogelmeier, Sara Barille, Elena Nudo, Victoria Carter, Derek Skinner, Rebecca Vella, George Georges

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