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RESEARCH IN FOCUS

Explore OPRI’s collection of published research on Oral Corticosteroid (OCS) use

PUBLICATIONS DATABASE

An Observational UK cohort study to describe intermittent oral corticosteroid prescribing patterns and their association with adverse outcomes in asthma

Thorax

27 December 2022

Heath Heatley, Trung N Tran, Arnaud Bourdin, Andrew Menzies-Gow, David Jackson, Ekaterina Maslova, Jatin Chapaneri, Derek Skinner, Victoria Carter, Jeffrey Shi Kai Chan, Cono Ariti, John Haughney, David Price

Patients with chronic obstructive pulmonary disease and evidence of eosinophilic inflammation experience exacerbations despite receiving maximal inhaled maintenance therapy

International Journal of Chronic Obstructive Pulmonary Disease

8 November 2022

Stephanie Chen, Marc Miravitlles, Chin Kook Rhee, Rupert Jones, Victoria Carter, Benjamin Emmanuel, Marianna Alacqua, David Price, Ian Pavord

Characterization of patients in the International Severe Asthma Registry with high steroid exposure who did or did not initiate biologic therapy (GLITTER I)

J Asthma Allergy

21 October 2022

Wenjia Chen, Mohsen Sadatsafavi, Trung N Tran, Ruth Murray, Nigel Chong Boon Wong, Nasloon Ali, Cono Ariti, Esther Garcia Gil, Anthony Newell, Marianna Alacqua, Mona Al-Ahmad, Alan Altraja, Riyad Al-Lehebi, Mohit Bhutani, Leif Bjermer, Anne Sofie Bjerrum, Arnaud Bourdin, Lakmini Bulathsinhala, Anna Von Bülow, John Busby, Giorgio Walter Canonica, Victoria Carter, George Christoff, Borja G Cosio, Richard Costello, Mark FitzGerald, João A Fonseca, Liam Heaney, Enrico Heffler, Mark Hew, Ole Hilberg, Flavia Hoyte, Takashi Iwanaga, David Jackson, Rupert Jones, Piotr Kuna, Désirée Larenas Linnemann, Sverre Lehmann, Lauri Lehtimäki, Juntao Lyu, Bassam Mahboub, Andrew Menzies-Gow, Concetta Sirena, Nikolaos Papadopoulos, Andriana Papaioannou, Diahn-Warng Perng (Steve), Matthew Peters, Celeste Porsbjerg, Todor Popov, Chin Kook Rhee, Sundeep Salvi, Camille Taillé, Christian Taube, Carlos Arturo Torres-Duque, Charlotte Suppli Ulrik, Seung Won Ra, Eileen Wang, Michael Wechsler, David Price, Mariko Koh, Jorge Máspero, Kwang Ha Yoo, Luis Perez de Llano, Paul E Peffler

Effect of stepping up to high-dose inhaled corticosteroids in patients with asthma

Journal of Allergy and Clinical Immunology

11 September 2022

Trung N Tran, Rupert Jones, Javier Nuevo, Maarten van den Berge, Guy Brusselle, Andrew Menzies-Gow, Derek Skinner, Victoria Carter, Janwillem Kocks, David Price, Ian Pavord

A pragmatic primary practice approach to allergy testing in asthma diagnosis, management, and referral

J Asthma Allergy

16 August 2022

Pascal Demoly, Andrew H. Liu, Pablo Rodriguez del Rio, Soren Pedersen, Thomas Casale, David Price

Asthma Exacerbations are Associated with a decline in Lung Function: A Longitudinal Population-Based Study

Thorax

3 August 2022

Seyi Soremekun, Liam Heaney, Derek Skinner, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Ruth Murray, Trung N Tran, Benjamin Emmanuel, Esther Garcia Gil, Andrew Menzies-Gow, Matthew Peters, Njira Lugogo, Rupert Jones, David Price, Naeimeh Hosseini, Neva Eleangovan

Characterisation of the Australian adult population living with asthma: Exacerbation frequency, long-term OCS use and adverse effects

Pragmatic and Observational Research

25 July 2022

Sinthia Bosnic-Anticevich, Mark Hew, Li Ping Chung, Biljana Cvetkovski, Scott Claxton, Peter Del Fante, Eve Denton, Joe Doan, Kanchanamala Ranasinghe, Lucy Morgan, Anita Sharma, Peter Smith, Deb Stewart, Philip J Thompson, Russell Wiseman, John Upham, Kwok Y Yan, Victoria Carter, Kiranjeet Dhillon, Florian Heraud, Thao Le, Rebecca Vella, David Price, John D Blakey, Kerry Hancock

Characterization of COPD in U.S. primary care: data from the Optimum Patient Care with DARTNet Research Database and the embedded Advancing the Patient Experience (APEX) in COPD registry

The Annals of Family Medicine

20 July 2022

Wilson Pace, Elias Brandt, Victoria Carter, Ku-Lang Chang, Chelsea Edwards, Alexander Evans, Chester Fox, Gabriela Gaona, MeiLan K Han, Alan Kaplan, Rachel Kent, Janwillem Kocks, Maja Kruszyk, Chantal Le Lievre, Tessa Li Voti, Cathy Mahle, Barry Make, Amanda Ratigan, Asif Shaikh, Neil Skolnik, Brooklyn Stanley, Barbara P Yawn, David Price

Biologics in severe asthma: the role of real-world evidence from registries

Eur Respir Rev

7 June 2022

Giovanni Paoletti, Jack Pepys, Marta Casini, Danilo Di Bona, Enrico Heffler, Celine Y.Y. Goh, David B. Price, Giorgio Walter Canonica

Variation in demographic and clinical characteristics of Patients with COPD receiving care in U.S. primary care: data from the Advancing the Patient EXperience (APEX) in COPD registry

Pragmatic and Observational Research

29 April 2022

Chester Fox, Wilson Pace, Elias Brandt, Victoria Carter, Ku-Lang Chang, Chelsea Edwards, Alexander Evans, Gabriela Gaona, MeiLan K Han, Alan Kaplan, Rachel Kent, Janwillem Kocks, Maja Kruszyk, Chantal Le Lievre, Tessa Li Voti, Cathy Mahle, Barry Make, Amanda Ratigan, Asif Shaikh, Neil Skolnik, Brooklyn Stanley, Barbara P Yawn, David Price

CONQUEST: a quality improvement program for defining and optimizing standards of care for modifiable high-risk COPD patients

Patient Related Outcome Measures

23 February 2022

Luis Alves, Rongchang Chen, Mark Dransfield, John Hurst, Fernando Martinez, Marc Miravitlles, Shigeo Muro, David Singh, Anita Sharma, Tonya Winders, Jonathan Marshall, Clementine Nordon, Michael Pollack, David Jones, Rupert Jones, Ruth Murray, Margee Kerr, Marije van Melle, Antony Hardjojo, Victoria Carter, Alexander Evans, Amy Couper, Rachel Pullen, Chris Price, David Price, Kostas Kostikas

Pub Med

Comparative safety of extrafine beclometasone fixed dose combinations (FDC) and fluticasone FDC in COPD

International Journal of Chronic Obstructive Pulmonary Disease

15 February 2022

David Price, William Henley, José Eduardo Delfini Cançado, Leonardo M. Fabbri, Huib AM Kerstjens, Alberto Papi, Nicolas Roche, Elif Şen, Dave Singh, Claus Vogelmeier, Sara Barille, Elena Nudo, Victoria Carter, Derek Skinner, Rebecca Vella, George Georges

Real-world biologic use and switch patterns in severe asthma: data from the International Severe Asthma Registry and the US CHRONICLE Study (SUNNIE)

J Asthma Allergy

13 January 2022

Andrew N. Menzies-Gow, Claire McBrien, Bindhu Unni, Celeste M. Porsbjerg, Mona Al-Ahmad, Christopher S. Ambrose, Karin Dahl Assing, Anna von Bülow, John Busby, Borja G. Cosio, J. Mark FitzGerald, Esther Garcia Gil, Susanne Hansen, Liam G. Heaney, Mark Hew, David J. Jackson, Maria Kallieri, Stelios Loukides, Njira Lugogo, Andriana I. Papaioannou, Désirée Larenas-Linnemann, Wendy C. Moore, Luis Perez-de-Llano, Linda M. Rasmussen, Johannes Schmid, Salman Siddiqui, Marianna Alacqua, Trung N. Tran, Charlotte Suppli Ulrik, John W. Upham, Eileen Wang, Lakmini Bulathsinhala, Victoria A. Carter, Isha Chaudhry, Neva Eleangovan, Ruth B. Murray, Chris A. Price, David B. Price

Measuring peak inspiratory flow in patients with chronic obstructive pulmonary disease

International Journal of Chronic Obstructive Pulmonary Disease

6 January 2022

Jill A. Ohar, Gary T. Ferguson, Donald A. Mahler, M. Bradley Drummond, Rajiv Dhand, Roy A. Pleasants, Antonio Anzueto, David Halpin, David Price, Gail S. Drescher, Haley M. Hoy, John Haughney, Michael W. Hess, Omar S. Usman

Global Variability in Administrative Approval Prescription Criteria for Biologic Therapy in Severe Asthma (BACS)

Journal of Allergy and Clinical Immunology: In Practice

3 January 2022

Celeste Porsbjerg, Andrew Menzies-Gow, Trung N Tran, Marianna Alacqua, Mona Al-Ahmad, Riyad Al-Lehebi, Alan Altraja, Andrey S. Belevskiy, Unnur Steina Björnsdóttir, Arnaud Bourdin, John Busby, Giorgio Walter Canonica, George Christoff, Borja G Cosio, Richard Costello, Mark FitzGerald, João A Fonseca, Susanne Hansen, Liam Heaney, Enrico Heffler, Mark Hew, Takashi Iwanaga, David Jackson, Janwillem Kocks, Maria Kallieri, Désirée Larenas Linnemann, Lauri Lehtimäki, Stelios Loukides, Njira Lugogo, Andriana Papaioannou, Paulo Márcio Pitrez, Todor Popov, Chin Kook Rhee, Mohsen Sadatsafavi, Johannes Martin Schmid, Salman Siddiqui, Camille Taillé, Christian Taube, Carlos Arturo Torres-Duque, Charlotte Suppli Ulrik, John Upham, Eileen Wang, Michael Wechsler, Ruth Murray, Bindhu Unni, Shi Ling Audrey Ang, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Mari-anne Rowlands, David Price, Job F.M. van Boven, Hsin-Kuo Ko, Mariko Koh, Jorge Máspero, Linda M Rasmussen, Luis Perez de Llano, Naeimeh Hosseini, Neva Eleangovan

Risk of pneumonia in patients with COPD initiating fixed dose inhaled corticosteroid (ICS) / long-acting bronchodilator (LABD) formulations containing extrafine beclometasone dipropionate versus patients initiating LABD without ICS

European Respiratory Society

25 November 2021

David Price, William Henley, José Eduardo Delfini Cançado, Leonardo M. Fabbri, Huib AM Kerstjens, Alberto Papi, Nicolas Roche, Elif Şen, Dave Singh, Claus Vogelmeier, Elena Nudo, Victoria Carter, Derek Skinner, Rebecca Vella, Joan B Soriano, Maxim Kots, George Georges

Impact of socioeconomic status on adult patients with asthma: a population-based cohort study from UK primary care (RADIANT)

J Asthma Allergy

10 November 2021

John Busby, David Price, Riyad Al-Lehebi, Sinthia Bosnic-Anticevich, Job FM van Boven, Benjamin Emmanuel, J Mark FitzGerald, Mina Gaga, Susanne Hansen, Mark Hew, Takashi Iwanaga, Désirée Larenas Linnemann, Bassam Mahboub, Patrick Mitchell, Daniela Morrone, Jonathan Pham, Celeste Porsbjerg, Nicolas Roche, Eileen Wang, Neva Eleangovan, Liam G Heaney

Type 2 Inflammatory Disease Burden Among Asthma Patients and its association with asthma-related outcomes

J Asthma Allergy

29 September 2021

David Price, Andrew Menzies-Gow, Claus Bachert, Giorgio Walter Canonica, Janwillem Kocks, Asif H. Khan, Fen Ye, Paul Rowe, Yufang Lu, Siddhesh Kamat, Victoria Carter, Jaco Voorham

Asthma phenotyping in primary care: applying the International Severe Asthma Registry eosinophil phenotype algorithm across all asthma severities

Journal of Allergy and Clinical Immunology: In Practice

14 August 2021

Marjan Kerkhof, Trung N Tran, Riyad Allehebi, Giorgio Walter Canonica, Liam Heaney, Mark Hew, Michael Wechsler, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Ruth Murray, Chris Price, David Price, Luis Perez de Llano, Neva Eleangovan

Persistence of eosinophilic asthma endotype and clinical outcomes: A real-world observational study

J Asthma Allergy

25 June 2021

Trung N Tran, Marjan Kerkhof, Victoria Carter, David Price

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