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RESEARCH IN FOCUS

Explore OPRI’s collection of published research on Oral Corticosteroid (OCS) use

PUBLICATIONS DATABASE

Cluster Randomized Trial Evaluating the Impact of Dual Bronchodilator with Add-on Sensor and Electronic Monitoring on Clinical Outcomes

Pragmatic and Observational Research

24 May 2021

David Price, Rupert Jones, Pascal Pfister, Hui Cao, Victoria Carter, Anu Kemppinen, Bjoern Holzhauer, Alan Kaplan, Allan Clark, David Halpin, Hilary Pinnock, James Chalmers, Job F.M. van Boven, Kai Beeh, Nicolas Roche, Omar Usmani, Paul Mastoridis, Kostas Kostikas

Eosinophilic and non-eosinophilic asthma: an expert consensus framework to characterize phenotypes in a global real-life severe asthma cohort

CHEST

19 April 2021

Liam Heaney, Mona Al-Ahmad, Vibeke Backer, John Busby, Giorgio Walter Canonica, George Christoff, Borja G Cosio, Mark FitzGerald, Enrico Heffler, Takashi Iwanaga, David Jackson, Andrew Menzies-Gow, Nikolaos Papadopoulos, Andriana Papaioannou, Todor Popov, Celeste Porsbjerg, Chin Kook Rhee, Mohsen Sadatsafavi, Yuji Tohda, Eileen Wang, Michael Wechsler, Marianna Alacqua, Alan Altraja, Leif Bjermer, Unnur Steina Björnsdóttir, Arnaud Bourdin, Guy Brusselle, Roland Buhl, Richard Costello, Mark Hew, Sverre Lehmann, Lauri Lehtimäki, Matthew Peters, Camille Taillé, Christian Taube, Trung N Tran, James Zangrilli, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Marjan Kerkhof, Ruth Murray, Chris Price, David Price, Mariko Koh, Luis Perez de Llano, Naeimeh Hosseini, Neva Eleangovan, Paul E Peffler

Cluster analysis of inflammatory biomarker expression in the International Severe Asthma Registry (BRISAR)

Journal of Allergy and Clinical Immunology: In Practice

18 March 2021

Eve Denton, David Price, Trung N Tran, Giorgio Walter Canonica, Andrew Menzies-Gow, Mark FitzGerald, Mohsen Sadatsafavi, Luis Perez de Llano, George Christoff, Anna Quinton, Chin Kook Rhee, Guy Brusselle, Charlotte Suppli Ulrik, Njira Lugogo, Fiona Hore-Lacy, Isha Chaudhry, Lakmini Bulathsinhala, Ruth Murray, Victoria Carter

Advancing the Patient EXperience (APEX) in COPD registry: Study Design and Strengths

The Journal of the American Board of Family Medicine

15 January 2021

Barbara P Yawn, Alan Kaplan, Wilson Pace, Janwillem Kocks, Lakmini Bulathsinhala, Victoria Carter, Ku-Lang Chang, Chelsea Edwards, Chester Fox, Gabriela Gaona, Gokul Gopalan, MeiLan K Han, Maja Kruszyk, Chantal Le Lievre, Cathy D. Mahle, Barry Make, Zoe K. Philip, Chris Price, Amanda Ratigan, Asif Shaikh, Neil Skolnik, Brooklyn Stanley, David Price

Development of the Advancing the Patient EXperience (APEX) in COPD registry: a modified Delphi Study

Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation

8 January 2021

Chelsea Edwards, Alan Kaplan, Barbara P Yawn, Janwillem Kocks, Lakmini Bulathsinhala, Victoria Carter, Ku-Lang Chang, Chester Fox, Gokul Gopalan, MeiLan K Han, Maja Kruszyk, Chantal Le Lievre, Cathy Mahle, Barry Make, Wilson Pace, Chris Price, Asif Shaikh, Neil Skolnik, David Price

Evaluating the Real-life Effect of MP-AzeFlu On Asthma Outcomes In Patients With Allergic Rhinitis and Asthma In UK Primary Care

World Allergy Organization Journal

19 December 2020

Hilda J.I. De Jong, Jaco Voorham, Glenis Scadding, Claus Bachert, Giorgio Walter Canonica, Peter Smith, Ulrich Wahn, Dermot Ryan, Jose A. Castillo, Victoria Carter, Ruth Murray, David Price

A comparison of the real-life clinical effectiveness of the leading licensed ICS/LABA combination inhalers in the treatment for COPD

International Journal of Chronic Obstructive Pulmonary Disease

26 November 2020

Simon Wan Yau Ming, John Haughney, Dermot Ryan, Iain Small, Federico Lavorini, Alberto Papi, Dave Singh, David Halpin, John Hurst, Shishir Patel, Matthias Ochel, Janwillem Kocks, Victoria Carter, Antony Hardjojo, David Price

Blood Eosinophil Count Predicts Treatment Failure and Hospital Readmission for COPD

ERJ Open Research

10 November 2020

Marjan Kerkhof, Isha Chaudhry, Ian Pavord, Marc Miravitlles, Chin Kook Rhee, David Halpin, Omar S. Usmani, Rupert Jones, Janwillem Kocks, Marianna Alacqua, Tamsin Morris, Alan Kaplan, David Price

Extra-fine beclometasone dipropionate/formoterol fumarate vs double bronchodilation therapy in patients with COPD: a historical real-world non-inferiority study

International Journal of Chronic Obstructive Pulmonary Disease

29 October 2020

Jaco Voorham, Simonetta Baldi, Luigi Santoro, Marjan Kerkhof, Marco Contoli, Leonardo M. Fabbri, Huib AM Kerstjens, Jose Luis López-Campos, Nicolas Roche, Dave Singh, Claus Vogelmeier, David Price

A multinational observational study exposing the burden and impact of self-reported concomitant rhinitis and identifying primary care patients at risk of asthma exacerbations

J Asthma Allergy

6 October 2020

Vicky Kritikos, David Price, Alberto Papi, Antonio Infantino, Björn Ställberg, Dermot Ryan, Federico Lavorini, Henry Chrystyn, John Haughney, Karin Lisspers Kevin Gruffydd-Jones, Miguel Román Rodríguez, Svein Høegh Henrichsen, Thys van der Molen, Victoria Carter, Sinthia Bosnic-Anticevich

Potential severe asthma hidden in UK primary care

Journal of Allergy and Clinical Immunology: In Practice

12 September 2020

Dermot Ryan, Heath Heatley, Liam Heaney, David Jackson, Paul E Peffler, John Busby, Andrew Menzies-Gow, Rupert Jones, Trung N Tran, Mona Al-Ahmad, Vibeke Backer, Manon Belhassen, Sinthia Bosnic-Anticevich, Arnaud Bourdin, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Neva Eleangovan, Mark FitzGerald, Peter G. Gibson, Naeimeh Hosseini, Alan Kaplan, Ruth Murray, Chin Kook Rhee, Eric Van Ganse, David Price

International severe asthma registry (ISAR): protocol for a global registry

BMC Medical Research Methodology

14 August 2020

Mark FitzGerald, Trung N Tran, Marianna Alacqua, Alan Altraja, Vibeke Backer, Leif Bjermer, Unnur Steina Björnsdóttir, Arnaud Bourdin, Guy Brusselle, Lakmini Bulathsinhala, John Busby, Giorgio Walter Canonica, Victoria Carter, Isha Chaudhry, You Sook Cho, George Christoff, Borja G Cosio, Richard Costello, Neva Eleangovan, Peter G. Gibson, Liam Heaney, Enrico Heffler, Mark Hew, Naeimeh Hosseini, Takashi Iwanaga, David Jackson, Rupert Jones, Mariko Koh, Thao Le, Lauri Lehtimäki, Dora Ludviksdottir, Anke-Hilse Maitland-van der Zee, Andrew Menzies-Gow, Ruth Murray, Nikolaos Papadopoulos, Luis Perez de Llano, Matthew Peters, Paul E Peffler, Todor Popov, Celeste Porsbjerg, Chris Price, Chin Kook Rhee, Mohsen Sadatsafavi, Yuji Tohda, Eileen Wang, Michael Wechsler, James Zangrilli, David Price

The long-term burden of COPD Exacerbations during Maintenance Therapy and Lung Function Decline

International Journal of Chronic Obstructive Pulmonary Disease

6 August 2020

Marjan Kerkhof, Jaco Voorham, Paul M Dorinsky, Claudia Cabrera, Patrick Darken, Janwillem Kocks, Mohsen Sadatsafavi, Don D Sin, Victoria Carter, David Price

Association between COPD exacerbations and lung function decline during maintenance therapy

Thorax

20 June 2020

Marjan Kerkhof, Jaco Voorham, Paul M Dorinsky, Claudia Cabrera, Patrick Darken, Janwillem Kocks, Mohsen Sadatsafavi, Don D Sin, David Price, Victoria Carter

Adequacy of therapy for people with both COPD and heart failure in the UK: historical cohort study

Pragmatic and Observational Research

2 June 2020

Kostas Kostikas, Chin Kook Rhee, John Hurst, Piergiuseppe Agostoni, Hui Cao, Robert Fogel, Rupert Jones, Janwillem Kocks, Karen Mezzi, Simon Wan Yau Ming, Ronan Ryan, David Price

A historical database cohort study addressing the clinical patterns prior to idiopathic pulmonary fibrosis (IPF) diagnosis in UK primary care

BMJ Open

30 May 2020

David R Thickett, Jaco Voorham, Ronan Ryan, Rupert Jones, Robina Coker, Andrew Wilson, Sen Yang, Mandy Ow, Priyanka Raju, Isha Chaudhry, Antony Hardjojo, Victoria Carter, David Price

Hormonal contraceptives and onset of asthma in reproductive-age women: population-based cohort study

Journal of Allergy and Clinical Immunology

15 April 2020

Bright I Nwaru, Rebecca Pillinger, Holly Tibble, Syed A. Shah, Dermot Ryan, Hilary Critchley, David Price, Catherine M Hawrlylowicz, Colin R Simpson, Ireneous N Soyiri, Francis Appiagyei, Aziz Sheikh

International Severe Asthma Registry: Mission Statement

CHEST

12 December 2019

Giorgio Walter Canonica, Marianna Alacqua, Alan Altraja, Vibeke Backer, Elisabeth Bel, Leif Bjermer, Unnur Steina Björnsdóttir, Arnaud Bourdin, Guy Brusselle, George Christoff, Borja G Cosio, Richard Costello, Mark FitzGerald, Peter G. Gibson, Liam Heaney, Enrico Heffler, Mark Hew, Takashi Iwanaga, Rupert Jones, Mariko Koh, Chin Kook Rhee, Sverre Lehmann, Lauri Lehtimäki, Dora Ludviksdottir, Anke-Hilse Maitland-van der Zee, Andrew Menzies-Gow, Nikolaos Papadopoulos, Vicente Plaza, Luis Perez de Llano, Matthew Peters, Celeste Porsbjerg, Mohsen Sadatsafavi, You Sook Cho, Yuji Tohda, Trung N Tran, Eileen Wang, James Zangrilli, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Neva Eleangovan, Naeimeh Hosseini, Thao Le, Ruth Murray, Chris Price, David Price

Characterization of Severe Asthma Worldwide: data from the International Severe Asthma Registry

CHEST

27 November 2019

Eileen Wang, Michael Wechsler, Trung N Tran, Liam Heaney, Rupert Jones, Andrew Menzies-Gow, John Busby, David Jackson, Paul E Peffler, Chin Kook Rhee, You Sook Cho, Giorgio Walter Canonica, Enrico Heffler, Peter G. Gibson, Mark Hew, Matthew Peters, Erin S Harvey, Marianna Alacqua, James Zangrilli, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Neva Eleangovan, Naeimeh Hosseini, Ruth Murray, David Price

Comparative safety profile of the fixed-dose combination corticosteroid and long-acting β2-agonist fluticasone propionate/formoterol fumarate: a 36-month longtiduinal cohort study in UK primary care

Drugs

20 November 2019

David Price, Victoria Carter, Jessica Martin, Elizabeth Gardener, Derek Skinner, Sen Yang, Matthias Hoffman

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