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RESEARCH IN FOCUS

Explore OPRI’s collection of published research on Oral Corticosteroid (OCS) use

PUBLICATIONS DATABASE

A comparison of the real-life clinical effectiveness of the leading licensed ICS/LABA combination inhalers in the treatment for COPD

International Journal of Chronic Obstructive Pulmonary Disease

26 November 2020

Simon Wan Yau Ming, John Haughney, Dermot Ryan, Iain Small, Federico Lavorini, Alberto Papi, Dave Singh, David Halpin, John Hurst, Shishir Patel, Matthias Ochel, Janwillem Kocks, Victoria Carter, Antony Hardjojo, David Price

Blood Eosinophil Count Predicts Treatment Failure and Hospital Readmission for COPD

ERJ Open Research

10 November 2020

Marjan Kerkhof, Isha Chaudhry, Ian Pavord, Marc Miravitlles, Chin Kook Rhee, David Halpin, Omar S. Usmani, Rupert Jones, Janwillem Kocks, Marianna Alacqua, Tamsin Morris, Alan Kaplan, David Price

Extra-fine beclometasone dipropionate/formoterol fumarate vs double bronchodilation therapy in patients with COPD: a historical real-world non-inferiority study

International Journal of Chronic Obstructive Pulmonary Disease

29 October 2020

Jaco Voorham, Simonetta Baldi, Luigi Santoro, Marjan Kerkhof, Marco Contoli, Leonardo M. Fabbri, Huib AM Kerstjens, Jose Luis López-Campos, Nicolas Roche, Dave Singh, Claus Vogelmeier, David Price

A multinational observational study exposing the burden and impact of self-reported concomitant rhinitis and identifying primary care patients at risk of asthma exacerbations

J Asthma Allergy

6 October 2020

Vicky Kritikos, David Price, Alberto Papi, Antonio Infantino, Björn Ställberg, Dermot Ryan, Federico Lavorini, Henry Chrystyn, John Haughney, Karin Lisspers Kevin Gruffydd-Jones, Miguel Román Rodríguez, Svein Høegh Henrichsen, Thys van der Molen, Victoria Carter, Sinthia Bosnic-Anticevich

Potential severe asthma hidden in UK primary care

Journal of Allergy and Clinical Immunology: In Practice

12 September 2020

Dermot Ryan, Heath Heatley, Liam Heaney, David Jackson, Paul E Peffler, John Busby, Andrew Menzies-Gow, Rupert Jones, Trung N Tran, Mona Al-Ahmad, Vibeke Backer, Manon Belhassen, Sinthia Bosnic-Anticevich, Arnaud Bourdin, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Neva Eleangovan, Mark FitzGerald, Peter G. Gibson, Naeimeh Hosseini, Alan Kaplan, Ruth Murray, Chin Kook Rhee, Eric Van Ganse, David Price

International severe asthma registry (ISAR): protocol for a global registry

BMC Medical Research Methodology

14 August 2020

Mark FitzGerald, Trung N Tran, Marianna Alacqua, Alan Altraja, Vibeke Backer, Leif Bjermer, Unnur Steina Björnsdóttir, Arnaud Bourdin, Guy Brusselle, Lakmini Bulathsinhala, John Busby, Giorgio Walter Canonica, Victoria Carter, Isha Chaudhry, You Sook Cho, George Christoff, Borja G Cosio, Richard Costello, Neva Eleangovan, Peter G. Gibson, Liam Heaney, Enrico Heffler, Mark Hew, Naeimeh Hosseini, Takashi Iwanaga, David Jackson, Rupert Jones, Mariko Koh, Thao Le, Lauri Lehtimäki, Dora Ludviksdottir, Anke-Hilse Maitland-van der Zee, Andrew Menzies-Gow, Ruth Murray, Nikolaos Papadopoulos, Luis Perez de Llano, Matthew Peters, Paul E Peffler, Todor Popov, Celeste Porsbjerg, Chris Price, Chin Kook Rhee, Mohsen Sadatsafavi, Yuji Tohda, Eileen Wang, Michael Wechsler, James Zangrilli, David Price

The long-term burden of COPD Exacerbations during Maintenance Therapy and Lung Function Decline

International Journal of Chronic Obstructive Pulmonary Disease

6 August 2020

Marjan Kerkhof, Jaco Voorham, Paul M Dorinsky, Claudia Cabrera, Patrick Darken, Janwillem Kocks, Mohsen Sadatsafavi, Don D Sin, Victoria Carter, David Price

Association between COPD exacerbations and lung function decline during maintenance therapy

Thorax

20 June 2020

Marjan Kerkhof, Jaco Voorham, Paul M Dorinsky, Claudia Cabrera, Patrick Darken, Janwillem Kocks, Mohsen Sadatsafavi, Don D Sin, David Price, Victoria Carter

Adequacy of therapy for people with both COPD and heart failure in the UK: historical cohort study

Pragmatic and Observational Research

2 June 2020

Kostas Kostikas, Chin Kook Rhee, John Hurst, Piergiuseppe Agostoni, Hui Cao, Robert Fogel, Rupert Jones, Janwillem Kocks, Karen Mezzi, Simon Wan Yau Ming, Ronan Ryan, David Price

A historical database cohort study addressing the clinical patterns prior to idiopathic pulmonary fibrosis (IPF) diagnosis in UK primary care

BMJ Open

30 May 2020

David R Thickett, Jaco Voorham, Ronan Ryan, Rupert Jones, Robina Coker, Andrew Wilson, Sen Yang, Mandy Ow, Priyanka Raju, Isha Chaudhry, Antony Hardjojo, Victoria Carter, David Price

Hormonal contraceptives and onset of asthma in reproductive-age women: population-based cohort study

Journal of Allergy and Clinical Immunology

15 April 2020

Bright I Nwaru, Rebecca Pillinger, Holly Tibble, Syed A. Shah, Dermot Ryan, Hilary Critchley, David Price, Catherine M Hawrlylowicz, Colin R Simpson, Ireneous N Soyiri, Francis Appiagyei, Aziz Sheikh

International Severe Asthma Registry: Mission Statement

CHEST

12 December 2019

Giorgio Walter Canonica, Marianna Alacqua, Alan Altraja, Vibeke Backer, Elisabeth Bel, Leif Bjermer, Unnur Steina Björnsdóttir, Arnaud Bourdin, Guy Brusselle, George Christoff, Borja G Cosio, Richard Costello, Mark FitzGerald, Peter G. Gibson, Liam Heaney, Enrico Heffler, Mark Hew, Takashi Iwanaga, Rupert Jones, Mariko Koh, Chin Kook Rhee, Sverre Lehmann, Lauri Lehtimäki, Dora Ludviksdottir, Anke-Hilse Maitland-van der Zee, Andrew Menzies-Gow, Nikolaos Papadopoulos, Vicente Plaza, Luis Perez de Llano, Matthew Peters, Celeste Porsbjerg, Mohsen Sadatsafavi, You Sook Cho, Yuji Tohda, Trung N Tran, Eileen Wang, James Zangrilli, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Neva Eleangovan, Naeimeh Hosseini, Thao Le, Ruth Murray, Chris Price, David Price

Characterization of Severe Asthma Worldwide: data from the International Severe Asthma Registry

CHEST

27 November 2019

Eileen Wang, Michael Wechsler, Trung N Tran, Liam Heaney, Rupert Jones, Andrew Menzies-Gow, John Busby, David Jackson, Paul E Peffler, Chin Kook Rhee, You Sook Cho, Giorgio Walter Canonica, Enrico Heffler, Peter G. Gibson, Mark Hew, Matthew Peters, Erin S Harvey, Marianna Alacqua, James Zangrilli, Lakmini Bulathsinhala, Victoria Carter, Isha Chaudhry, Neva Eleangovan, Naeimeh Hosseini, Ruth Murray, David Price

Comparative safety profile of the fixed-dose combination corticosteroid and long-acting β2-agonist fluticasone propionate/formoterol fumarate: a 36-month longtiduinal cohort study in UK primary care

Drugs

20 November 2019

David Price, Victoria Carter, Jessica Martin, Elizabeth Gardener, Derek Skinner, Sen Yang, Matthias Hoffman

A multinational observational study identifying primary care patients at risk of overestimation of asthma control

NPJ Primary Care Respiratory Medicine

5 November 2019

Vicky Kritikos, David Price, Alberto Papi, Antonio Infantino, Björn Ställberg, Dermot Ryan, Federico Lavorini, Henry Chrystyn, John Haughney, Karin Lisspers, Kevin Gruffyd-Jones, Miguel Román Rodríguez, Svein Høegh Henrichsen, Thys van der Molen, Victoria Carter, Sinthia Bosnic-Anticevich

Inhaled corticosteroids in COPD and onset of type 2 diabetes and osteoporosis: matched cohort study

NPJ Primary Care Respiratory Medicine

28 October 2019

David Price, Jaco Voorham, Guy Brusselle, Andreas Clemens, Kostas Kostikas, Jeffrey W. Stephens, Hye Yun Park, Nicolas Roche, Robert Fogel

Does changing inhaler device impact real-life asthma outcomes clinical and economic evaluation

Journal of Allergy and Clinical Immunology: In Practice

5 October 2019

Chin Kook Rhee, Job F.M. van Boven, Simon Wan Yau Ming, Hye Yun Park, Deog Kyeom Kim, Hae-Sim Park, Joanna Ling Zhi Jie, Kwang Ha Yoo, David Price

Management of community-acquired pneumonia: an observational study in UK primary care

Pragmatic and Observational Research

23 September 2019

Naomi Launders, Dermot Ryan, Christopher C Winchester, Derek Skinner, Priyanka Raju Konduru, David Price

Comparative effectiveness of triple therapy versus dual bronchodilation in COPD

ERJ Open Research

30 August 2019

Jaco Voorham, Massimo Corradi, Alberto Papi, Claus Vogelmeier, Dave Singh, Leonardo M. Fabbri, Marjan Kerkhof, Janwillem Kocks, Victoria Carter, David Price

Association of elevated fractional exhaled nitric oxide concentration and blood eosinophil count with severe asthma exacerbation

Clinical and Translational Allergy

21 August 2019

David Price, Sinthia Bosnic-Anticevich, Ian Pavord, Nicolas Roche, David Halpin, Leif Bjermer, Usmani OS, Guy Brusselle, Ming SWY, Rastogi S

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