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Asthma patients in Greece found to have fewer asthma exacerbations and steroid-related diseases compared to global patterns in new study from ISAR
Greek patients with severe asthma were found to have a notably lower asthma exacerbation rate compared with patients globally, while long-term oral corticosteroid (LTOCS) use, and importantly evidence of steroid-related disease, was substantially lower in Greece compared with Southern Europe and global rates. Differences in severe asthma characteristics, treatment patterns, and disease control between Greece, Southern Europe, and the global population have been identified in
May 192 min read
Beyond RCTs: Real-World Data Reveals Common Downstream Pathways to Severe Asthma Exacerbations
Pathways that predict severe asthma attacks (exacerbations) were found to be similar, with matching strength of prediction, in both clinical trials (Randomised Controlled Trials, RCTs) and real-world data (RWD) settings in the new International Severe Asthma Registry (ISAR) study “Interactive Pathways of Key Prognostic Factors in Severe Asthma: A Bayesian Network Comparison of Clinical Trials & Real-World Data”. Recently published in CHEST, this study performed a novel Bayesi
Apr 133 min read
Mexico vs Global Severe Asthma Study Shows Steroid Reduction Benefits and Need for Targeted Treatments
Long-term oral corticosteroid (LTOCS) use has been found to be lower in Mexican patients than globally and may be associated with impact to critical health outcomes, with potentially oral corticosteroid-related diseases found to be less common in Mexican patients. These findings are reported in the real-world study, “ Severe asthma patients’ characteristics in Mexico versus International Severe Asthma Registry (ISAR) Global ” , recently published in Current Allergy and Asthma
Mar 243 min read
Type 2 (T2)-targeted biologics have utility in the management of T2-low asthma, but more effective therapies are needed: Implications of EMBER study
The real-world study, “ Response to biologics along a gradient of T2 involvement in patients with severe asthma: a data-driven biomarker clustering approach ”, was recently published in The Journal of Allergy and Clinical Immunology: In Practice . Five biomarker clusters along a gradient of T2 involvement were identified using a data-driven approach instead of the pre-defined thresholds used in prior studies. Biologic use (Anti-IgE, Anti-IL5/5R and Anti-IL4Rα) was associated
Oct 14, 20253 min read
A recent study shows a surprising improvement in respiratory outcomes when patients with asthma receive weight loss drugs.
Singapore, [10 April 2025] – A large real world evidence study conducted by leading respiratory experts found patients with asthma who...
Apr 8, 20252 min read
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